Path2Models: large-scale generation of computational models from biochemical pathway maps

• Author(s): Büchel, Finja ; Rodriguez, Nicolas ; Swainston, Neil ; Wrzodek, Clemens ; Czauderna, Tobias ; Keller, Roland ; Mittag, Florian ; Schubert, Michael ; Glont, Mihai ; Golebiewski, Martin ; van Iersel, Martijn ; Keating, Sarah ; Rall, Matthias ; Wybrow, Michael ; Hermjakob, Henning ; Hucka, Michael ; Kell, Douglas B ; Müller, Wolfgang ; Mendes, Pedro ; Zell, Andreas ; Chaouiya, Claudine ; Saez-Rodriguez, Julio ; Schreiber, Falk ; Laibe, Camille ; Dräger, Andreas ; Le Novère, Nicolas
• Date: 2013
• Persistent ID: http://hdl.handle.net/10400.7/436
• Origin: ARCA - Access to Research and Communication Annals
• Subject(s): Modular rate law; Constraint based models; Logical models; SBGN; SBML
• Document Type: Journal article
• Language: English
• Contributor(s): ARCA

Description

Systems biology projects and omics technologies have led to a growing number of biochemical pathway models and reconstructions. However, the majority of these models are still created de novo, based on literature mining and the manual processing of pathway data.