Document details

FAAH rs324420 polymorphism is associated with performance in elite rink-hockey players

Author(s): Silva, Hugo-Henrique ; Tavares, Valéria ; Silva, Maria Raquel ; Neto, Beatriz Vieira ; Cerqueira, Fátima ; Medeiros, R.

Date: 2022

Persistent ID: http://hdl.handle.net/10284/11040

Origin: Repositório Institucional - Universidade Fernando Pessoa

Subject(s): Elite athlete; Rink-hockey; Gene; Polymorphism; Sport; Performance; Success


Description

Genetic factors are among the major contributors to athletic performance. Although more than 150 genetic variants have been correlated with elite athlete status, genetic foundations of competition-facilitating behavior influencing elite performances are still scarce. This is the first study designed to examine the distribution of genetic determinants in the athletic performance of elite rink-hockey players. A total of 116 of the world’s top best rink-hockey players (28.2 ± 8.7 years old; more than 50% are cumulatively from the best four world teams and the best five Portuguese teams), who participated at the elite level in the National Rink-Hockey Championship in Portugal, were evaluated in anthropometric indicators/measurements, training conditions, sport experience and sport injuries history. Seven genetic polymorphisms were analyzed. Polymorphism genotyping was performed using the TaqMan® Allelic Discrimination Methodology. Rink-hockey players demonstrated significantly different characteristics according to sex, namely anthropometrics, training habits, sports injuries and genetic variants, such as Vitamin D Receptor (VDR) rs731236 (p < 0.05). The Fatty Acid Amide Hydrolase (FAAH) rs324420 A allele was significantly associated with improved athletic performance (AA/AC vs. CC, OR = 2.80; 95% Cl, 1.23–6.35; p = 0.014; p = 0.008 after Bootstrap) and confirmed as an independent predictor among elite rink-hockey players (adjusted OR = 2.88; 95% Cl, 1.06–7.80; p = 0.038). Our results open an interesting link from FAAH-related biology to athletic performance.

Document Type Journal article
Language English
Contributor(s) Repositório Institucional da Fernando Pessoa
facebook logo  linkedin logo  twitter logo 
mendeley logo

Related documents