Bacteriophage Phi 6 as surrogate and human-harmless viruses to study anti-SARS-CoV-2 approaches

• Author(s): Barros, Joana ; Monteiro, Fernando ; Ferraz, Maria Pia
• Date: 2021
• Persistent ID: http://hdl.handle.net/10284/9718
• Origin: Repositório Institucional - Universidade Fernando Pessoa
• Subject(s): SARS-CoV-2; COVID-19; Bacteriophage Φ6
• Document Type: Journal article
• Language: English
• Contributor(s): Repositório Institucional da Fernando Pessoa

Description

Given safety challenges in conducting laboratory work with highly infectious human coronaviruses (pathogenicity, genetic mutations rate, biosafety level 3 and 4 requirements), many researchers have valued the potential of bacteriophages as appropriate viral surrogate to measure humans enveloped virus’ survival, transfer and removal. The use of phage Φ6 seems to be useful as coronavirus surrogate to assess the effectiveness of anti-SARS-CoV-2 approaches, providing important insights concerning COVID-19 pandemic and human public health.