Oral Anticoagulation in the Elderly: New Oral Anticoagulants-Innovative Solution for an Old Problem?

• Author(s): Barbosa, M ; Menezes Falcão, L
• Date: 2016
• Persistent ID: http://hdl.handle.net/10400.26/15173
• Origin: Hospital de Vila Franca de Xira
• Subject(s): Idoso; Anticoagulantes; Administração Oral
• Document Type: Journal article
• Language: English
• Contributor(s): Repositório Comum

Description

Direct oral anticoagulants emerge as the most innovative and promising drug toward preventing and treating cardiovascular disease, raising great interest among the scientific community. Numerous studies and meta-analysis generated much data clarifying clinicians' doubts; however, uncertainties remain regarding their use in particular groups such as patients with prosthetic valves, in valvular atrial fibrillation (defined as atrial fibrillation related to mitral rheumatic heart disease or prosthetic heart valves), among the elderly, in paraneoplastic thromboembolism, in pulmonary embolism with hemodynamic compromise, and scarcity of specific antidotes. This review article intends to condense the vast scientific production addressing new oral anticoagulants by focusing on their advantages and disadvantages when used on the elderly.