Author(s): Zarrabeitia, María T. ; Pinheiro, Fátima ; de Pancorbo, Marian M. ; Cainé, Laura ; Cardoso, Sergio ; Gusmão, Leonor ; Riancho, José A.
Date: 2009
Persistent ID: http://hdl.handle.net/10400.26/44628
Origin: Instituto Nacional de Medicina Legal e Ciências Forenses, IP
Subject(s): Genetics, Population; Female; Genetic Markers; Genes, X-Linked
We have applied a recently described X-STRs decaplex to characterize four population groups of the Iberian Peninsula, including two well mixed populations and two relatively isolated ones from Northern Spain, in order to get a better insight about the characteristics of X-STRs in those population types between-population differences in allelic frequencies were relatively small. Nevertheless, Fst values were between 0.2 and 2.7%, figures higher than usually reported for autosomic STRs. This result suggests that when forensic cases originate from relatively isolated groups in western Europe, and a specific reference database is not available, it is probably safe to include a Fst-based correction in the calculations of matching or kinship probabilities.
