Autor(es): Spínola, C. ; Bruges-Armas, J. ; Brehm, A. ; Spínola, H.
Data: 2008
Identificador Persistente: http://hdl.handle.net/10400.13/2152
Origem: DigitUMa - Repositório da Universidade da Madeira
Assunto(s): HLA-A; Sequence-based typing; Sub-Saharan populations; Guinea-Bissau; .; Faculdade de Ciências da Vida
Human leukocyte antigen (HLA)-A locus polymorphisms were examined at highresolution level, using sequence-based typing, in the four most representative Guinea-Bissau(NorthwestAfrica)ethnicgroups:Balanta,Bijago´ s,FulaandPapel. DespitetheFulagrouphavingsignificantdifferenceswhencomparedwiththeother three ethnic groups, all four groups most likely received a genetic input from non sub-Saharans. The Bijago´ s and Papel groups showed similarities to neighboring populations from Mali and Senegal. The Balanta, despite their oral tradition of an East Africa origin, show affinities to Cameroon populations, highly influenced by Bantu migrations. These results are congruent with historical sources and other genetic studies that support the finding that the Guinea-Bissau genetic pool was influenced by several migrations from North Africa, Sahara and East Africa.
