Autor(es): Zhu, Beitong ; Wu, Xiaoli ; Rodrigues, João ; Hu, Xichao ; Sheng, Ruilong ; Bao, Guang-Ming
Data: 2021
Identificador Persistente: http://hdl.handle.net/10400.13/4088
Origem: DigitUMa - Repositório da Universidade da Madeira
Assunto(s): Fluorescent probe; Dual-analytes; N2H4; ClO−; Bioimaging; Living cells; .; Faculdade de Ciências Exatas e da Engenharia; Centro de Química da Madeira
Hydrazine (N2H4) and ClO− are very harmful for public health, hence it is important and necessary to monitor them in living cells. Herein, we rationally designed and synthesized a dual-analytes responsive fluorescent sensor PTMQ for distinguishing detection of N2H4 and ClO−. PTMQ underwent N2H4-induced double bond cleavage, affording colorimetric and green fluorescence enhancement with good selectivity and a low detection limit (89 nM). On the other hand, PTMQ underwent ClO−-induced sulfur oxidation and displayed red fluorescence lighting-up response towards ClO− with good selectivity, rapid response (<0.2 min) and a low detection limit (58 nM). Moreover, PTMQ was successfully employed for in-situ imaging of N2H4 and ClO− in living cells
