Document details

A novel histopathological scoring system to distinguish urticarial vasculitis from chronic spontaneous urticaria

Author(s): Puhl, Viktoria ; Bonnekoh, Hanna ; Scheffel, Jörg ; Hawro, Tomasz ; Weller, Karsten ; von den Driesch, Peter ; Röwert-Huber, Hans-Joachim ; Cardoso, José ; Gonçalo, Margarida ; Maurer, Marcus ; Krause, Karoline

Date: 2021

Persistent ID: https://hdl.handle.net/10316/100863

Origin: Estudo Geral - Universidade de Coimbra

Subject(s): chronische sponstane urtikaria; endothelzellschwellung; erythrozyten-extravasate; fibrin; histopathologie; leukozytoklasie; urtikariavaskulitis


Description

Urticarial vasculitis (UV) is defined by long-lasting urticarial lesions combined with the histopathologic findings of leukocytoclastic vasculitis. As one of the major unmet needs in UV, diagnostic criteria are rather vague and not standardized. Moreover, there seems to be considerable overlap with chronic spontaneous urticaria (CSU), particularly for the normocomplementemic variant of UV. Therefore, this study aimed to develop a diagnostic scoring system that improves the histopathologic discrimination between UV and CSU.

Document Type Journal article
Language English
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