Author(s):
Puhl, Viktoria ; Bonnekoh, Hanna ; Scheffel, Jörg ; Hawro, Tomasz ; Weller, Karsten ; von den Driesch, Peter ; Röwert-Huber, Hans-Joachim ; Cardoso, José ; Gonçalo, Margarida ; Maurer, Marcus ; Krause, Karoline
Date: 2021
Persistent ID: https://hdl.handle.net/10316/100863
Origin: Estudo Geral - Universidade de Coimbra
Subject(s): chronische sponstane urtikaria; endothelzellschwellung; erythrozyten-extravasate; fibrin; histopathologie; leukozytoklasie; urtikariavaskulitis
Description
Urticarial vasculitis (UV) is defined by long-lasting urticarial lesions combined with the histopathologic findings of leukocytoclastic vasculitis. As one of the major unmet needs in UV, diagnostic criteria are rather vague and not standardized. Moreover, there seems to be considerable overlap with chronic spontaneous urticaria (CSU), particularly for the normocomplementemic variant of UV. Therefore, this study aimed to develop a diagnostic scoring system that improves the histopathologic discrimination between UV and CSU.