Metabolic mitochondrial alterations prevail in the female rat heart 8 weeks after exercise cessation

• Autor(es): Tocantins, Carolina ; Martins, João D ; Rodrigues, Óscar M ; Grilo, Luís F ; Diniz, Mariana S. ; Stevanovic-Silva, Jelena ; Beleza, Jorge ; Coxito, Pedro ; Rizo-Roca, David ; Santos-Alves, Estela ; Rios, Manoel ; Carvalho, Lina ; Moreno, António J ; Ascensão, António ; Magalhães, José ; Oliveira, Paulo J ; Pereira, Susana P
• Data: 2023
• Identificador Persistente: https://hdl.handle.net/10316/108719
• Origem: Estudo Geral - Universidade de Coimbra
• Assunto(s): cardiac remodelling; exercise cessation; female; high-fat high-sugar diet; metabolic dysfunction; mitochondria
• Tipo de Documento: Artigo científico
• Idioma: Português

Descrição

The consumption of high-caloric diets strongly contributes to the development of non-communicable diseases (NCDs), including cardiovascular disease, the leading cause of mortality worldwide. Exercise (along with diet intervention) is one of the primary non-pharmacological approaches to promote a healthier lifestyle and counteract the rampant prevalence of NCDs. The present study evaluated the effects of exercise cessation after a short period training on the cardiac metabolic and mitochondrial function of female rats.