Author(s): Pereira, Neide ; Brinca, Ana ; Manuel Brites, Maria ; José Julião, Maria ; Tellechea, Óscar ; Gonçalo, Margarida
Date: 2012
Persistent ID: http://hdl.handle.net/10316/109849
Origin: Estudo Geral - Universidade de Coimbra
Subject(s): Pityriasis lichenoides et varioliformis acuta; Erythromycin; Methylprednisolone
We report a case of a 63-year-old man hospitalized for a polymorphous generalized eruption consisting of maculopapules with peripheral scaling, vesicopustules, and ulceronecrotic and crusted lesions measuring 5-20 mm, localized on his trunk and extremities, particularly exuberant in the flexural area. Histopathology showed necrotic keratinocytes with exocytosis of red blood cells and lymphocytes and a dermal perivascular and periadnexal inflammatory infiltrate, composed of CD8+/CD4-/CD30- T cells, indicating the clinical diagnosis of pityriasis lichenoides et varioliformis acuta. He was treated with erythromycin and methylprednisolone reduced gradually over 5 months, with a slow but complete response; the patient was without lesions after 2 years of follow-up. The authors want to remind of this rare entity which may present difficulties in diagnosis and therapy.
