Autor(es):
Freire, Ana Paula Coelho Figueira ; Amin, Shaan ; de Lira, Fábio Santos ; Morano, Ana Elisa von Ah ; Pereira, Telmo ; Coelho-e-Silva, Manuel João ; Caseiro, Armando ; Christofaro, Diego Giulliano Destro ; Dos Santos, Vanessa Ribeiro ; Júnior, Osmar Marchioto ; Pinho, Ricardo Aurino ; Silva, Bruna Spolador de Alencar
Data: 2023
Identificador Persistente: https://hdl.handle.net/10316/113962
Origem: Estudo Geral - Universidade de Coimbra
Assunto(s): COVID-19; SARS-CoV-2; exercise; autonomic nervous system; sympathetic nervous system; parasympathetic nervous system; COVID-19 vaccination; post-acute sequelae of COVID-19; communicable diseases; Humans; Young Adult; Recovery of Function; Case-Control Studies; Follow-Up Studies; SARS-CoV-2; Autonomic Nervous System; Exercise; Immunization; Heart Rate; COVID-19
Descrição
Coronavirus disease 2019 (COVID-19) has detrimental multi-system consequences. Symptoms may appear during the acute phase of infection, but the literature on long-term recovery of young adults after mild to moderate infection is lacking. Heart rate variability (HRV) allows for the observation of autonomic nervous system (ANS) modulation post-SARS-CoV-2 infection. Since physical activity (PA) can help improve ANS modulation, investigating factors that can influence HRV outcomes after COVID-19 is essential to advancements in care and intervention strategies. Clinicians may use this research to aid in the development of non-medication interventions. At baseline, 18 control (CT) and 20 post-COVID-19 (PCOV) participants were observed where general anamnesis was performed, followed by HRV and PA assessment. Thus, 10 CT and 7 PCOV subjects returned for follow-up (FU) evaluation 6 weeks after complete immunization (two doses) and assessments were repeated. Over the follow-up period, a decrease in sympathetic (SNS) activity (mean heart rate: p = 0.0024, CI = -24.67--3.26; SNS index: p = 0.0068, CI = -2.50--0.32) and increase in parasympathetic (PNS) activity (mean RR: p = 0.0097, CI = 33.72-225.51; PNS index: p = 0.0091, CI = -0.20-1.47) were observed. At follow-up, HRV was not different between groups (p > 0.05). Additionally, no differences were observed in PA between moments and groups. This study provides evidence of ANS recovery after SARS-CoV-2 insult in young adults over a follow-up period, independent of changes in PA.
(CNPq)—Brazil and the Coordination for the Improvement of Higher Education Personnel (CAPES)—Brazil (code 001), São Paulo Research Foundation (FAPESP)/Brazil.
