Autor(es): Melo, Teresa M. V. D. Pinho e ; Cardoso, Ana L. ; Gomes, Clara S. B. ; Gonsalves, António M. d'A. Rocha
Data: 2003
Identificador Persistente: https://hdl.handle.net/10316/5158
Origem: Estudo Geral - Universidade de Coimbra
Assunto(s): 2H-azirines; 1,3-dipolar cycloaddition; 3H-pyrazole; pyrimidine
2H-Azirine-3-carboxylates unsubstituted at C-2 act as dipolarophiles in the reaction with diazomethane giving new 4,5-dihydro-3H-pyrazole derivatives. The synthesis of a pyrimidine was also achieved via 1,3-dipolar cycloaddition of methyl 2-bromo-3-phenyl-2H-azirine-2-carboxylate with an azomethine ylide.
http://www.sciencedirect.com/science/article/B6THS-493P1M1-17/1/5df1370edad7138f3cae89fadd9b5c4d
