Ethyl 7-Acetyl-8a-methyl-3-(1-phenyl-1H-tetrazol-5-yl)-1,4,4a,5,6,8a-hexahydro-7H-pyrano[2,3-c]pyridazine-1-carboxylate

• Autor(es): Lopes, Susana M. M. ; Lemos, Américo ; Paixão, José A. ; Melo, Teresa M. V. D. Pinho e
• Data: 2022
• Identificador Persistente: https://hdl.handle.net/10316/98811
• Origem: Estudo Geral - Universidade de Coimbra
• Assunto(s): tetrazoles; diaza-1,3-butadiene; pyrano[2,3-c]pyridazine; methyl vinyl ketone dimer; diels-alder reactions; X-ray structure
• Tipo de Documento: Artigo científico
• Idioma: Inglês

Descrição

The Diels–Alder reaction of ethyl 3-(1-phenyl-1H-tetrazol-5-yl-1,2-diaza-1,3-butadiene- 1-carboxylate with 2-acetyl-6-methyl-2,3-dihydro-4H-pyran (methyl vinyl ketone dimer) regios- electively afforded the corresponding 3-(tetrazol-5-yl)-hexahydro-7H-pyrano[2,3-c]pyridazine in quantitative yield. An X-ray crystal structure of this cycloadduct is reported.