Author(s): Gomes, Sttefany Viana ; Dias, Bruna Vidal ; Pereira, Renata Rebeca ; Lúcio, Karine de Pádua ; Souza, Débora Maria Soares de ; Silva, André Talvani Pedrosa da ; Brandão, Geraldo Célio ; Cosenza, Gustavo Pereira ; Queiroz, Karina Barbosa de ; Costa, Daniela Caldeira
Date: 2020
Origin: Oasisbr
Subject(s): Inflammation; Polyunsaturated fatty acid; Saturated fatty acid; Vegetable oils
Our goal was to carry out a comparative study to evaluate the metabolic and inflammatory effects and the redox status of commercial vegetable oils supplementation [linseed (LO), coconut (VCO), and sunflower (SO)] in metabolically healthy rats. The results found in this study showed that the LO group decreased the HOMA-IR and hepatic cholesterol, and increased the serum levels of IL-6. Supplementation with VCO increased glucose and HOMA-IR, cholesterol concentration and serum triacylglycerol (TAG). In this group, there was also an increase in TBARS. In the SO group there was a decrease in serum concentrations of cholesterol and TAG and an increase in hepatic concentration of these lipids. In addition, in the SO group there was a decrease in hepatic and sérum concentrations of IL-6 and hepatic levels of TNF, as well as a decrease in the GSH/GSSG ratio, suggesting changes in glutathione metabolism and inflammatory mediators.
