Autor(es): Souza, Ana Maria Alves de ; Guarda, Vera Lúcia de Miranda ; Leite, Lucia Fernanda Cavalcanti da Costa ; Barbosa Filho, José Maria ; Lima, Maria do Carmo Alves de ; Galdino, Suely Lins ; Pitta, Ivan da Rocha
Data: 2014
Origem: Oasisbr
Assunto(s): Benzothiazines; Benzylidene benzothiazines; AM1 conformational and configurational analysis
The synthesis and physico-chemical properties of new 6-acetylamino or 6-benzoyl-amino 2-benzylidene-4-methyl-4Hbenzo[1,4]thiazin-3-ones and 6-benzoylamino or 6-nitro 2-benzylidene-4H-benzo[1,4]thiazin-3-ones are described. These benzylidene benzothiazine compounds were prepared by the Knoevenagel condensation with benzaldehydes. The configurations and conformations of benzylidene benzothiazine derivatives were optimised using the semi-empirical method AM1.
