Prevalence of vitamin D deficiency and its relationship with factors associated with recurrent wheezing

• Author(s): Peçanha, Mirna Brito ; Freitas, Rodrigo de Barros ; Moreira, Tiago Ricardo ; Silva, Luiz Sérgio ; Oliveira, Leandro Licursi de ; Cardoso, Silvia Almeida
• Date: 2019
• Origin: Oasisbr
• Subject(s): Vitamin D; Asthma; Respiratory sounds; Minors
• Document Type: Journal article
• Language: English

Description

To determine the prevalence of vitamin D deficiency/insufficiency in children 0-18 years of age with recurrent wheezing and/or asthma residing in the microregion of Viçosa, Minas Gerais, Brazil, and treated at a referral center, and to determine its association with major risk factors for wheezing. A cross-sectional study was performed using a semi-structured questionnaire, which was administered by trained interviewers to the legal guardians of the study participants. Data were obtained regarding general characteristics of recurrent wheezing; general sociodemographic, environmental, and biologic factors; and atopy-related factors. The magnitude of the statistical association was assessed by calculating ORs and their corresponding 95% CIs by using multiple logistic regression. We included 124 children in the study. The prevalence of vitamin D deficiency/insufficiency in the sample was 57.3%. Vitamin D deficiency/insufficiency was found to be associated with wheezing in the first year of life, personal history of atopic dermatitis, environmental pollution, and vitamin D supplementation until 2 years of age. The prevalence of vitamin D deficiency/insufficiency was high in our sample. Vitamin D concentrations were directly associated with vitamin D supplementation until 2 years of age and were inversely associated with wheezing events in the first year of life, personal history of atopic dermatitis, and environmental pollution.