Document details

In silico study of the anti-obesity potential of Baccharis trimera phenolic compounds

Author(s): Souza, Wanderson Fernando Mello de ; Baptista, Andrea Regina de Souza ; Machado, Ricardo Luiz Dantas ; Rocha, Cristiane Barbosa ; Moreira, Ricardo Felipe Alves

Date: 2019

Origin: Oasisbr

Subject(s): Epicatechin; Bacharis trimera; non-volatile compounds; flavonoids


Description

Obesity is a worldwide public health problem. Regular exercises, balanced diet, allopathic and herbal medicines can be employed in the prevention and treatment of this pathological condition.  Regarding the alternative treatment of obesity using medicinal plants, Baccharis trimera deserves attention due to the anti-obesity properties associated with its methanolic extracts.  This in silico study aims to evaluate in which phenolic compounds of this plant the anti-obesity potential is most remarkable.  According to the results obtained by the employment of some bioinformatics tools, the flavonoid known as epicatechin is probably the most important  anti-obesity principle found in Baccharis trimera.

Document Type Journal article
Language English
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