Adult nesidioblastosis.

• Author(s): Branco, Vítor A ; Santos, Rui M ; Cipriano, M Augusta ; Tralhão, Guilherme ; Otero, M ; Moura, José A ; Sousa, F Castro ; Porto, Armando
• Date: 2003
• Origin: Acta Médica Portuguesa
• Document Type: Journal article
• Language: Portuguese

Description

In adults, endogenous hyperinsulinemic hypoglycaemia is almost invariably due to insulinoma. The authors describe a 29 year old patient with repeated postprandial symptomatic hypoglycaemias and negative prolonged fast test. Distal pancreatectomy was performed, directed by positive arteriographic testing. Histological examination revealed pancreatic nesidioblastosis and no tumoral lesion. Distinct pathogenetic, clinical, diagnostic and therapeutic aspects of this rare disease in the adult are reviewed.

In adults, endogenous hyperinsulinemic hypoglycaemia is almost invariably due to insulinoma. The authors describe a 29 year old patient with repeated postprandial symptomatic hypoglycaemias and negative prolonged fast test. Distal pancreatectomy was performed, directed by positive arteriographic testing. Histological examination revealed pancreatic nesidioblastosis and no tumoral lesion. Distinct pathogenetic, clinical, diagnostic and therapeutic aspects of this rare disease in the adult are reviewed.