Acute renal failure and nephrotic syndrome after maneb exposure. A new case with light and electron microscopic study.

• Author(s): de Carvalho, E ; Faria, V ; Loureiro, A ; Miranda, V
• Date: 1989
• Origin: Acta Médica Portuguesa
• Document Type: Journal article
• Language: Portuguese

Description

A new case of nephrotoxic effect of Maneb is related. The patient used this product as fungicide and developed a progressive illness with acute renal failure. The study by light and electron microscopy revealed severe tubular lesions that disappeared some months later with tubular cell regeneration. However, in spite of the renal function returning to normal, a steroid-dependent nephrotic syndrome persisted with glomerular minimal change like lesions.

A new case of nephrotoxic effect of Maneb is related. The patient used this product as fungicide and developed a progressive illness with acute renal failure. The study by light and electron microscopy revealed severe tubular lesions that disappeared some months later with tubular cell regeneration. However, in spite of the renal function returning to normal, a steroid-dependent nephrotic syndrome persisted with glomerular minimal change like lesions.