Autor(es): Shaw, Jeffrey Jon ; Ishikawa, Edna Aoba Yassui ; Lainson, Ralph ; Braga, Roseli Ribeiro ; Silveira, Fernando Tobias
Data: 2017
Origem: Oasisbr
Assunto(s): Leishmania / classifica??o; Leishmania / isolamento & purifica??o; Ecossistema Amaz?nico; Brasil (BR)
The Wellcome Trust, London and the Funda??o Nacional de Sa?de of the Brazilian Ministry of Health, Brasilia.
Minist?rio da Sa?de. Funda??o Nacional de Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil.
Minist?rio da Sa?de. Funda??o Nacional de Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil.
Minist?rio da Sa?de. Funda??o Nacional de Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil.
Minist?rio da Sa?de. Funda??o Nacional de Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil.
Minist?rio da Sa?de. Funda??o Nacional de Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil.
Leishmania (Viannia) shawi Lainson, Braga, de Souza, P?voa, Ishikawa & Silveira, 1989, was originally recorded from monkeys (Cebus apella and Chiropotes satanas), sloths (Choloepus didactylus and Bradypus tridactylus) and coatis (Nasua nasua) and the sandfly, Lutzomyia whitmani. With a panel of Leishmania specific monoclonal antibodies, it was found that 30.5 per cent of the Leishmania strains from patients, who had contracted cutaneous leishmaniasis in Par? State, were similar, but not identical to L. (V.) guyanensis. The enzyme profiles of 18 of these strains were determined, and it was found that 12 isolates belonged to the same zymodeme as the type strain of L. (V.) shawi. The other 6 belonged to a second L. (V.) shawi zymodeme that only differed from the other by having a slightly faster PEP band. These results are the first records of infections of L. (V.) shawi in man and suggest that this parasite is probably common in areas of Par? State to the south of the Amazon River.
