Autor(es):
Guzman, Hilda ; Contreras-Guti?rrez, Maria Angelica ; Rosa, Am?lia Paes de Andrade Travassos da ; Nunes, Marcio Roberto Teixeira ; Cardoso, Jedson Ferreira ; Popov, Vsevolod L ; Young, Katherine I ; Savit, Chelsea ; Wood, Thomas G ; Widen, Steven G ; Watts, Douglas M ; Hanley, Kathryn A ; Perera, David ; Fish, Durland ; Vasilakis, Nikos ; Tesh, Robert B
Data: 2018
Origem: Oasisbr
Assunto(s): Flavivirus; Arbovirus / classifica??o; Culicidae; Flaviviridae; Arbovirus / isolamento & purifica??o; Peru; Mal?sia (Sarawak)
Descrição
This work was funded in part by grant R24AI120942 and by contract HHSN272201000040I/HHSN27200004/D04 from the National Institutes of Health and a pilot grant by the Institute of Human Infections and Immunity. MAC was supported by a Programa de Doctorados Nacionales-Colciencias (Convocatoria 567) Ph.D. fellowship.
University of Texas Medical Branch. Department of Pathology and Institute for Human Infection and Immunity. Galveston, TX, USA.
Universidad de Antioquia. Sede de Investigacion Universitaria. Programa de Estudio y Control de Enfermedades Tropicales. Medellin, Colombia.
University of Texas Medical Branch. Department of Pathology and Institute for Human Infection and Immunity. Galveston, TX, USA.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Centro de Inova??es Tecnol?gicas. Ananindeua, PA, Brasil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Centro de Inova??es Tecnol?gicas. Ananindeua, PA, Brasil / Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Programa de P?s-Gradua??o em Virologia. Ananindeua, PA, Brazil.
University of Texas Medical Branch. Department of Pathology and Institute for Human Infection and Immunity. Galveston, TX, USA.
New Mexico State University. Department of Biology. Las Cruces, New Mexico.
University of Washington. School of Public Health. Seattle, Washington, USA / Yale University. Department of Ecology and Evolutionary Biology. New Haven, Connecticut, USA.
University of Texas Medical Branch. Department of Biochemistry and Molecular Biology. Galveston, TX, USA.
University of Texas Medical Branch. Department of Biochemistry and Molecular Biology. Galveston, TX, USA.
University of Texas at El Paso. Border Biomedical Research Center. El Paso, TX, USA / U.S. Naval Medical Research Unit-6. Callao, Peru.
New Mexico State University. Department of Biology. Las Cruces, New Mexico.
Universiti Malaysia Sarawak. Institute of Health and Community Medicine. Kota Samarahan, Sarawak, Malaysia.
Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, Connecticut, USA.
University of Texas Medical Branch. Department of Pathology and Institute for Human Infection and Immunity. Galveston, TX, USA.
University of Texas Medical Branch. Department of Pathology and Institute for Human Infection and Immunity. Galveston, TX, USA.
Three novel insect-specific flaviviruses, isolated from mosquitoes collected in Peru, Malaysia (Sarawak), and the United States, are characterized. The new viruses, designated La Tina, Kampung Karu, and Long Pine Key, respectively, are antigenically and phylogenetically more similar to the mosquito-borne flavivirus pathogens, than to the classical insect-specific viruses like cell fusing agent and Culex flavivirus. The potential implications of this relationship and the possible uses of these and other arbovirus-related insect-specific flaviviruses are reviewed.
