Autor(es): Brasiliense, Danielle Murici ; Lima, Karla Val?ria Batista ; P?rez-Chaparro, Paula Juliana ; Mamizuka, Elsa Masae ; Souza, Cintya de Oliveira ; Dutra, Livia Maria Guimar?es ; McCulloch, John Anthony
Data: 2018
Origem: Oasisbr
Assunto(s): Carbapen?micos / antagonistas & inibidores; Acinetobacter / isolamento & purifica??o; Acinetobacter / gen?tica; Infec??o hospitalar; Resist?ncia Microbiana a Medicamentos; Recombina??o Gen?tica / gen?tica; gene blaOXA-72
This work was supported by S?o Paulo Research Foundation grant 2013/12107-4, CNPq grants 457421/2014-2 and 485438/2012-7, and Instituto Evandro Chagas/Secretaria de Vigil?ncia em Sa?de/ Minist?rio da Sa?de (Ministry of Health), Brazil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Laborat?rio de Biologia Molecular. Ananindeua, PA, Brasil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Laborat?rio de Biologia Molecular. Ananindeua, PA, Brasil.
Universidade de S?o Paulo.Faculdade de Farm?cia. Departamento de An?lises Cl?nicas e Toxicol?gicas. S?o Paulo, SP, Brazil.
Universidade de S?o Paulo.Faculdade de Farm?cia. Departamento de An?lises Cl?nicas e Toxicol?gicas. S?o Paulo, SP, Brazil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Laborat?rio de Biologia Molecular. Ananindeua, PA, Brasil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Laborat?rio de Biologia Molecular. Ananindeua, PA, Brasil.
Universidade de S?o Paulo.Faculdade de Farm?cia. Departamento de An?lises Cl?nicas e Toxicol?gicas. S?o Paulo, SP, Brazil / National Cancer Institute, National Institutes of Health. Cancer and Inflammation Program. Trinchieri Lab. Bethesda, MD, USA.
We sought to characterize the genetic context of blaOXA-72 gene in a carbapenem-resistant Acinetobacter pittii strain recovered from a hospitalized patient from Bel?m, North Brazil, in the Amazon region. We found that the blaOXA-72 gene was carried by a small plasmid, pIEC338SCox, that is 10,498?bp. The gene is flanked by XerC/XerD-like recombinase sites, which suggests that this gene was acquired onto this plasmid by recombination.
