Autor(es): Mac?do, olinda ; Freitas, Felipe Bonfim ; Reis, Raimundo Macedo dos ; Bensabath, Gilberta ; Nunes, Heloisa Marceliano ; Siqueira, Jones Anderson Monteiro ; Gabbay, Yvone Benchimol
Data: 2020
Origem: Oasisbr
Assunto(s): S?ndrome de Imunodefici?ncia Adquirida / patologia; HIV / patogenicidade; Preval?ncia; Migra??o Humana; T?cnicas Imunoenzim?ticas / m?todos; Minera??o; Marab? (PA); Parauapebas (PA); Curion?polis (PA); Cana? dos Caraj?s (PA); Complexo Caraj?s (PA)
This research was supported by Vale do Rio Doce Company and Evandro Chagas Institute (IEC), and the payment of English review was done by the Virology P?s-Graduation Program of IEC.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
Acquired immunodeficiency syndrome (AIDS) caused by human immunodeficiency virus (HIV) is a major global public health problem. The aim of this study is to determine the prevalence of HIV-1 infection in four municipalities of Par? State (Marab?, Parauapebas, Curion?polis, and Cana? dos Caraj?s), in northern, Brazil. The municipalities are located in the Caraj?s Complex iron mining area. The employment opportunities result in extensive migratory flow of people. A total of 4771 serum samples were obtained from 2005 to 2014 and were sent to Evandro Chagas Institute, Bel?m-Par?, where they were tested by enzyme-linked immunosorbent assay, with reactive samples confirmed by Western blot analysis. The samples were from individuals from 23 Brazilian states and the Federal District, mainly Maranh?o (39.53%) and other municipalities of Par? (34.25%). The total positivity rate was 0.48% (23/4771). The rate was 0.47% (14/2975) in males and 0.50% (9/1796) in females. Of these, 0.33% (14/4275) were from asymptomatic individuals whose serum were collected during the serological survey, 1.81% (9/497) were from cases featuring clinical symptoms including fever/diarrhea/jaundice, which were included in febrile, diarrheal, and icteric syndromes analyzed during the study. The findings indicated the presence of HIV-1 infection in the general population studied. The majority of cases (60.9%, 14 of 23 positive cases) were asymptomatic.
