Autor(es): Mesquita, Cristal Ribeiro ; Concei??o, Emilyn Costa ; Monteiro, L?cia Helena Martins Tavares ; Silva, Odinea Maria da ; Lima, Luana Nepomuceno Gondim Costa ; Oliveira, Rafael Aleixo Coelho de ; Brito, Artemir Coelho de ; Guimar?es, Ricardo Jos? de Paula Souza e ; Lima, Karla Val?ria Batista
Data: 2021
Origem: Oasisbr
Assunto(s): Tuberculose / diagn?stico; Monitoramento Epidemiol?gico; Epidemiologia / tend?ncias; An?lise Espacial; Medidas em Epidemiologia; Ilha de Maraj? (PA)
Funding: This research was funded by the National Council for the Improvement of Higher Education (CAPES), grant number 1660892 and the Amazon Foundation for Support to Studies and Research (FAPESPA), grant number 88887.358315.
Universidade do Estado do Par?. Programa de P?s-Gradua??o em Biologia Parasit?ria na Amaz?nia. Bel?m, PA, Brazil / Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Programa de P?s-Gradua??o em Epidemiologia e Vigil?ncia em Sa?de. Ananindeua, PA, Brasil / Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
Funda??o Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Programa de P?s-Gradua??o em Pesquisa Cl?nica em Doen?as Infecciosas. Rio de Janeiro, RJ, Brazil.
Secretaria de Sa?de do Estado do Par?. Belem, PA, Brazil.
Secretaria de Sa?de do Estado do Par?. Belem, PA, Brazil.
Universidade do Estado do Par?. Programa de P?s-Gradua??o em Biologia Parasit?ria na Amaz?nia. Bel?m, PA, Brazil / Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Programa de P?s-Gradua??o em Epidemiologia e Vigil?ncia em Sa?de. Ananindeua, PA, Brasil / Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
Universidade Federal do Par?. Programa de P?s-Gradua??o em Sa?de, Ambiente e Sociedade. Belem, PA, Brazil.
Coordena??o Geral de Vigil?ncia das Doen?as de Transmiss?o Respirat?ria de Condi??es Cr?nicas. Rio de Janeiro, PA, Brazil.
Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Programa de P?s-Gradua??o em Epidemiologia e Vigil?ncia em Sa?de. Ananindeua, PA, Brasil .
Universidade do Estado do Par?. Programa de P?s-Gradua??o em Biologia Parasit?ria na Amaz?nia. Bel?m, PA, Brazil / Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
Abstract: Tuberculosis (TB) is an infectious communicable disease, which despite global efforts, still needs special attention in regions with difficult access. This study aims to describe the spatial and epidemiological trends of TB incidences from 2013 to 2018 in Maraj? Island, the Amazonian region, Par?, Brazil. We have obtained secondary data from the Brazilian TB databases and performed geospatial and statistical analyses on the data for new TB cases, relapses, and re-admissions. From 2013 to 2018, 749 new cases were reported, in which the diagnostics (culture) was not performed for 652 (87.2%) patient samples, the drug resistance test (DST) was performed for nine (1.2%) samples, and one (0.13%) was multidrug-resistant TB (MDR-TB). The rapid molecular testing (RMT) was performed on 40 (5.3%) patient samples, with results indicating that eight (20%) were susceptible to rifampicin and two (5%) were rifampicin resistant. Overall, the cure rate was 449 (66.7%), while relapses and re-admissions were 41 and 44, respectively. On the geospatial distribution, the municipality of Soure stands out with a high number of incidences, relapses, and re-admissions. Spatially, the eight MDR cases were randomly distributed. Our data highlight the urgent need for TB control measures in this region, by introducing the Xpert-Ultra? MTB/RIF (Cepheid, Sunnyvale, CA, United States) and Ogawa-Kudoh.
