Author(s): Oliveira, Luís M. ; Goncalves, T. M. ; Botelho, A. R. ; Martins, I. S. ; Silva, H. F. ; Carneiro, I. ; Carvalho, S. ; Henrique, R. ; Tuchin, V. V.
Date: 2022
Persistent ID: http://hdl.handle.net/10400.22/22344
Origin: Repositório Científico do Instituto Politécnico do Porto
Subject(s): Absorption coefficient spectrum; Melanin; Lipofuscin; Tissue aging; Cancer development
The direct calculation of the absorption coefficient spectra of various tissues from spectral measurements allowed to retrieve the contents of melanin and lipofuscin. In the rabbit brain cortex, 1.8 times higher melanin content is explained by the neuron degeneration process. Similar melanin and lipofuscin contents were found in the rabbit pancreas as a result of the tissue aging process. The conversion of 83 % of the melanin in the human normal kidney into lipofuscin in the cancer kidney indicates that lipofuscin can be considered a kidney cancer marker in humans.
