Genetic variants at the Wnt/[beta]-catenin and oestrogen receptor signalling pathways are associated with low bone mineral density in dancers

• Author(s): Amorim, Tânia ; Durães, Cecília ; Maia, José ; Machado, José Carlos ; Nogueira, Luísa ; Adubeiro, Nuno ; Flouris, Andreas D. ; Metsios, George S. ; Marques, Franklim ; Wyon, Matthew ; Koutedakis, Yiannis
• Date: 2016
• Persistent ID: http://hdl.handle.net/10400.22/26710
• Origin: Repositório Científico do Instituto Politécnico do Porto
• Subject(s): Wnt/[beta]-catenin; Bone Mineral Density
• Document Type: Conference object
• Language: English
• Contributor(s): REPOSITÓRIO P.PORTO

Description

Research suggests that dancers are at higher risk of developing low bone mineral density (BMD) compared with the general population. However, the associated factors contributing to low BMD in dancers are not fully understood. We aimed to assess the association of single-nucleotide polymorphisms (SNPs) in the Wnt/b-catenin and oestrogen receptor (ER) signalling pathways with low BMD in dancers.