Efficacy and safety of Tocilizumab in the treatment of Rheumatoid Arthritis: An umbrella review

• Author(s): Silva, David ; Moreira, Fernando ; Santos, Marlene ; Moreira, Fernando
• Date: 2025
• Persistent ID: http://hdl.handle.net/10400.22/30628
• Origin: Repositório Científico do Instituto Politécnico do Porto
• Subject(s): Immune system; Tumor immunology; Autoimmune disease
• Document Type: Conference paper
• Language: English
• Contributor(s): REPOSITÓRIO P.PORTO

Description

Tocilizumab (TCZ) is a humanized immunoglobulin G1 monoclonal antibody that targets and inhibits the interleukin-6 (IL-6) receptor. As a selective inhibitor of this cytokine, TCZ offers a targeted approach in managing inflammatory conditions. Given its specificity and potential therapeutic benefits, this article aims to provide a comprehensive summary of the efficacy and safety of TCZ in the treatment of RA.