Author(s): Sadahiro, Aya ; Feresin Moraes, José Roberto ; Hue Moraes, Maria Elisa ; Romero, Matilde ; Lima Gouvea, Nancy Alves de ; Gouvea, Celso José ; Ogusku, Maurício Morishi ; Campbell, Iphis Tenfuss ; Zaitz, Clarisse
Date: 2020
Origin: Oasisbr
Subject(s): Trichophyton Rubrum
The frequency of HLA (Human Leucocyte Antigens) was analyzed in 25 non-consanguineous Brazilian Ashkenazic Jews, resident in the city of São Paulo, Brazil, suffering from chronic dermatophytosis caused by T. rubrum, and in 25 non-infected individuals belonging to the same ethnic group. Statistically significant values (p<0.05) were observed for HLA-B14 associated with resistance to chronic dermatophytosis and HLA-DQB1*06 (p=0.05) possibly related to susceptibility. These findings suggest that genes on the chromosome 6, in the region of the major histocompatibility complex, may influence the development of chronic dermatophytosis.
