Autor(es): Pereira, L ; Gonçalves, J ; Bandelt, H-J
Data: 2008
Identificador Persistente: http://hdl.handle.net/10216/109569
Origem: Repositório Aberto da Universidade do Porto
Assunto(s): Asthenozoospermia/enzymology; Asthenozoospermia/genetics; Asthenozoospermia/physiopathology; DNA Mitochondrial; Genotype; Haplotypes; Humans; Male; Mitochondria/enzymology; Mutation; NADH Dehydrogenase/genetics; Oligospermia; Phenotype; Portugal; Sperm Motility/genetics; Spermatozoa/enzymology
It has recently been suggested that a hitherto unobserved mutation, C11994T, causes oligoasthenozoospermia in men from India but at the same time does not affect systems other than the motility of the sperm. There are good reasons to question this proposition, in view of the worldwide mtDNA database and the Indian record in particular. We have further analyzed the oligoasthenozoospermic samples from a previous systematic study of infertile Portuguese men and found no instance of C11994T.
