Autor(es):
Eijkemans, M ; Mommers, M ; Harskamp-van Ginkel, MW ; Vrijkotte, TGM ; Ludvigsson, J ; Faresjö, Å ; Bergström, A ; Ekström, S ; Grote, V ; Koletzko, B ; Bønnelykke, K ; Eliasen, AU ; Bager, P ; Melbye, M ; Annesi-Maesano, I ; Baïz, N ; Barros, H ; Santos, AC ; Duijts, L ; Mensink-Bout, SM ; Flexeder, C ; Koletzko, S ; Schikowski, T ; Eggesbø, MÅ ; Lenters, V ; Fernández-Tardón, G ; Subiza-Perez, M ; Garcia-Aymerich, J ; López-Vicente, M ; Sunyer, J ; Torrent, M ; Ballester, F ; Kelleher, C ; Mehegan, J ; Berg, AV ; Herberth, G ; Standl, M ; Kuehni, CE ; Pedersen, ESL ; Jansen, M ; Gehring, U ; Boer, JMA ; Devereux, G ; Turner, S ; Peltola, V ; Lagström, H ; Inskip, HM ; Pike, KC ; Dalmeijer, GW ; Ent, CKV ; Thijs, C
Data: 2024
Identificador Persistente: https://hdl.handle.net/10216/161431
Origem: Repositório Aberto da Universidade do Porto
Descrição
OBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study. DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined. SETTING: Children aged 0-18 years from 26 European birth cohorts. PARTICIPANTS: 136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood. MAIN OUTCOME MEASURE: Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity) at age 6-18 years. RESULTS: Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results. CONCLUSIONS: Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood. © Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
