Lower Free Triiodothyronine Levels Within the Reference Range Are Associated with Higher Cardiovascular Mortality: an Analysis of the NHANES

• Autor(es): Neves, JS ; Leitão, L ; Baeta Baptista, R ; Bigotte Vieira, M ; Magriço, R ; Viegas Dias, C ; Oliveira, A ; Falcão-Pires, I ; Lourenço, A ; Carvalho, D ; Leite-Moreira, A
• Data: 2019
• Identificador Persistente: http://hdl.handle.net/10400.17/3496
• Origem: Repositório do Centro Hospitalar de Lisboa Central, EPE
• Assunto(s): Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Cause of Death; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Nutrition Surveys; Portugal; Reference Values; Retrospective Studies; Risk Assessment; Risk Factors; Survival Rate; Triiodothyronine; Young Adult; HCC NEF; HDE PED
• Tipo de Documento: Artigo científico
• Idioma: Inglês
• Contribuidor(es): Repositório da Unidade Local de Saúde São José

Descrição

Thyroid hormones play a central role in cardiovascular homeostasis. Lower free triiodothyronine (FT3) levels have been associated with worse prognosis in several conditions. However, contrary to thyrotropin (TSH) and free thyroxine (FT4), the role of FT3 in morbidity and mortality in the general population remains uncertain. Our objective was to evaluate the association between within the normal range FT3 levels and mortality in the general population.