Author(s): Soares, L ; Matos, A ; Mello Vieira, M ; Cruz, R ; Caixas, U
Date: 2022
Persistent ID: http://hdl.handle.net/10400.17/4329
Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
Subject(s): HSJ MED; Constitutional Symptoms and Sle; Lupus Lymphadenitis; Lupus Lymphadenopathy; Lymphadenopathy
Lymphadenopathy (LAP) is a common but nonspecific feature of many diseases, representing a vast spectrum of etiologies such as infectious or inflammatory diseases, malignancies, and drugs. In systemic lupus erythematosus (SLE), it can be the first manifestation. We present the case of a 20-year-old female with a history of fever, night sweats, anorexia, and asthenia for five months. She also had diffuse generalized LAP. Although malignant etiologies were our major concern, an extensive workup for malignancy and infections was unrevealing. However, an autoimmune workup led to the diagnosis of SLE. This case shows that SLE can present as generalized LAP with constitutional symptoms, and hence it should be considered in the differential diagnosis.
