Detalhes do Documento

Endobronchial Amphotericin B to Treat Hemoptysis in an Inoperable Patient with Aspergillosis

Autor(es): Pinto, M ; Rodrigues, J ; Silva, M ; Maia, D ; Miguel, A

Data: 2024

Identificador Persistente: http://hdl.handle.net/10400.17/4913

Origem: Repositório do Centro Hospitalar de Lisboa Central, EPE

Assunto(s): HSM PNEU; Amphotericin B; Aspergilloma; Flexible Bronchoscopy; Hemoptysis; Pulmonary Aspergillosis


Descrição

A 37-year-old man presented with chronic cavitary pulmonary aspergillosis and hemoptysis refractory to systemic antifungal therapy with voriconazole and bronchial artery embolization. Surgical excision was unfeasible due to the patient's refusal of blood transfusions. Ten sessions of intracavitary instillation of amphotericin B via flexible bronchoscopy were then performed. Hemoptysis cessation and aspergilloma resolution were achieved, with no toxicity or side effects, and the clinical benefits were sustained at six months of follow-up.

Tipo de Documento Artigo científico
Idioma Inglês
Contribuidor(es) Repositório da Unidade Local de Saúde São José
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