Transcontinental dissemination of the L2b/D-Da recombinant Chlamydia trachomatis Lymphogranuloma venereum (LGV) strain: need of broad multi-country molecular surveillance

• Author(s): Borges, Vítor ; Isidro, Joana ; Correia, Cristina ; Cordeiro, Dora ; Vieira, Luís ; Lodhia, Zohra ; Fernandes, Cândida ; Rodrigues, Ana Maria ; Azevedo, Jacinta ; Alves, João ; Roxo, João ; Rocha, Miguel ; Côrte-Real, Rita ; Toscano, Cristina ; Pessanha, Maria Ana ; Nissan, Israel ; Pilo, Shlomo ; Rorman, Efrat ; Dveyrin, Zeev ; Paitan, Yossi ; Paran, Haim ; Wagner-Kolasko, Gal ; Beirnes, Jennifer ; Gibbons, Suzanne ; Severini, Alberto ; Borrego, Maria José ; Gomes, João Paulo
• Date: 2021
• Persistent ID: http://hdl.handle.net/10400.18/7991
• Origin: Repositório Científico do Instituto Nacional de Saúde
• Subject(s): Chlamydia trachomatis; Fluoroquinolones Resistance; Intercontinental Dissemination; Lymphogranuloma Venereum (LGV); Recombination; Infecções Sexualmente Transmissíveis; Resistência aos Antimicrobianos
• Document Type: Journal article
• Language: English
• Contributor(s): Repositório Científico do Instituto Nacional de Saúde

Description

Previously, we identified a Chlamydia trachomatis Lymphogranuloma venereum (LGV) recombinant strain possessing a unique non-LGV ompA genotype. Here, culture-independent genome sequencing confirms its circulation in Europe, Middle East and North America, and unveils genetic evidence of emergence of antibiotic resistance. Multi-country and systematic molecular surveillance is needed.