Author(s): Slezakova, Klara ; Cavaleiro-Rufo, J. ; Esteves, F. ; Costa, D. ; Pereira, M.C. ; Teixeira, J.P. ; Madureira, J.
Date: 2023
Persistent ID: http://hdl.handle.net/10400.18/9019
Origin: Repositório Científico do Instituto Nacional de Saúde
Subject(s): Volatile Organic Compounds; Electronic Nose; Multivariate Analysis; Ar e Saúde Ocupacional
Breath analysis using an electronic nose (eNose) is a technology for exhaled volatile organic compounds (VOCs) that has shown potential in the diagnosis of respiratory diseases. However, the effect of an individual’s characteristics in the exhaled VOCs profile is far from fully understood. This pilot study aimed to identify the relevant characteristics of participants that may influence the VOCs profiles by the eNose. The study population consisted of 91 volunteers (57.1% males) with an average age of 38 years, randomly recruited among nonexposed individuals to VOCs in Porto, Portugal. Exhaled breath air samples were analysed using the Cyranose® 320. Physiological (e.g. height, weight) and sociodemographic characteristics, behavioural patterns, and occupational/environmental exposures were collected through a self-administered questionnaire. Other data (e.g. type of consumed food, liquids and oral hygiene) was recorded via face-to-face interviews. Results showed that exhaled VOCs profiles are influenced by water intake prior to breath sample air collection. It is suggested that individuals should abstain from drinking water for 2.5 h before VOC analysis. This work will support other ongoing research in occupational exposure scenarios, such as forest firefighters’, to further the understanding of this under-explored scientific area, since we hypothesise that VOCs patterns will differ between persons occupationally exposed to VOCs and those unexposed.
