Autor(es):
Pereira, Jorge C. ; Machado, Ana ; Saianda, Mafalda ; Gonçalves-Anjo, Nuno ; Bastos, Estela ; Orge, Leonor ; Rocha, Sara ; Figueira, Luís ; Matos, Ana Cristina ; Silva, João ; Mendonça, Paula ; Carvalho, Paulo ; Tavares, Paula ; Lima, Carla ; Alves, Anabela ; Esteves, Alexandra ; Pinto, Maria de Lurdes ; Pires, Isabel ; Gama, Adelina ; Sargo, Roberto ; Silva, Filipe ; Seixas, Fernanda ; Pinto, Madalena Vieira ; Pires, Maria dos Anjos
Data: 2022
Identificador Persistente: http://hdl.handle.net/10400.11/8751
Origem: Repositório Científico do Instituto Politécnico de Castelo Branco
Assunto(s): Chronic Wasting Disease; Cervidae; Portugal
Descrição
The chronic wasting disease (CWD) in cervids is now a rising concern in wildlife within Europe, since the first case detected in Norway in 2016, 40 more appear until May of 2022, in Norway, Sweden and Finland. The unclear origin of these new European cases and the risk that CWD poses to cohabiting ani-mals or more importantly to humans is largely unknown, is very important for the establishment of risk assessment projects, even in countries with no cases of CWD to forecast possible infections. In this way, a synergistic collaborative project was established between the UTAD, INIAV and IPCB to evaluate the risk of a potential occurrence of CWD in cervid Portuguese populations. The study of prion protein gene, PRNP, has been proved to be a valuable tool for determining the relative susceptibility to TSEs since this is influenced by polymorphisms in this gene. The aim of this work is the screening for PrPresand determina-tion of the PRNP genotyping profile on Portuguese cervids, as the survey and georeferencing of these ani-mals will contribute to delineating the risk of dissemi-nation of CWD in Portugal.
