Author(s):
Botura, Mariana Borges ; Santos, Jener David Gonçalves dos ; Silva, Gisele D. da ; Lima, Hélimar G. de ; Oliveira, João Victor A. de ; Almeida, Maria Angela Ornelas de ; Batatinha, Maria José Moreira ; Branco, Alexsandro ; Botura, Mariana Borges ; Santos, Jener David Gonçalves dos ; Silva, Gisele D. da ; Lima, Hélimar G. de ; Oliveira, João Victor A. de ; Almeida, Maria Angela Ornelas de ; Batatinha, Maria José Moreira ; Branco, Alexsandro
Date: 2013
Origin: Oasisbr
Subject(s): Agave sisalana; Anthelmintic; Flavonoids; Saponins; Goats
Description
Texto completo. Acesso restrito. p. 211–217
Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-07-01T20:13:03Z No. of bitstreams: 1 7777777777777777777.pdf: 547229 bytes, checksum: c8608a2a26ddbc99fa2efa3742f57f05 (MD5)
Approved for entry into archive by Alda Lima da Silva(sivalda@ufba.br) on 2013-08-16T19:12:06Z (GMT) No. of bitstreams: 1 7777777777777777777.pdf: 547229 bytes, checksum: c8608a2a26ddbc99fa2efa3742f57f05 (MD5)
Made available in DSpace on 2013-08-16T19:12:06Z (GMT). No. of bitstreams: 1 7777777777777777777.pdf: 547229 bytes, checksum: c8608a2a26ddbc99fa2efa3742f57f05 (MD5) Previous issue date: 2013
This study describes the in vitro anthelmintic activity of aqueous extracts (AE), ethyl acetate extracts (EE), flavonoid fractions (FF) and saponin fractions (SF) obtained from sisal waste (Agave sisalana) against gastrointestinal nematodes of goats. The activity of these extracts was evaluated by performing inhibition of egg hatch (EHA) and larval migration (LMI) assays. The EC50 results of the EHA corresponded to 4.7, 0.1 and 0.05 mg/mL for EE, EA and FF, respectively. The SF fraction showed no ovicidal activity. The percent efficacies that were observed for the LMI were 50.3, 33.2 and 64.1% for the AE, EE and SF, respectively. The FF fraction did not show activity against the larvae. The analysis of the FF fraction indicates the presence of a homoisoflavonoid. This report suggests that the A. sisalana has activity in vitro against gastrointestinal nematodes of goats. This effect is likely related to the presence of homoisoflavonoid and saponin compounds, which have different actions for specific stages of nematode development.
Salvador
