Autor(es): Cordeiro, Soraia Machado ; Neves, Alan B. ; Ribeiro, Cássio T. ; Petersen, Maya L. ; Gouveia, Edilane L. ; Ribeiro, Guilherme S., et al. ; Cordeiro, Soraia Machado ; Neves, Alan B. ; Ribeiro, Cássio T. ; Petersen, Maya L. ; Gouveia, Edilane L. ; Ribeiro, Guilherme S., et al.
Data: 2013
Origem: Oasisbr
Assunto(s): Meningococcal Disease; Meningitis; Neisseria; Meningitidis; Serogroup; Epidemiology; Brazil
Submitted by Maria Creuza Silva (mariakreuza@yahoo.com.br) on 2013-11-29T13:50:39Z No. of bitstreams: 1 Guilherme Ribeiro. Hospital-based surveillance of meningococcal...2007.pdf: 309275 bytes, checksum: dbcafcc44d2a91e8c0fefe33b65ca928 (MD5)
Made available in DSpace on 2013-11-29T13:50:39Z (GMT). No. of bitstreams: 1 Guilherme Ribeiro. Hospital-based surveillance of meningococcal...2007.pdf: 309275 bytes, checksum: dbcafcc44d2a91e8c0fefe33b65ca928 (MD5) Previous issue date: 2007
This study aimed to describe the clinical, epidemiological and microbiological features of meningococcal meningitis in Salvador, Brazil. Between February 1996 and January 2001, a hospital based surveillance prospectively identified cases of culture-positive meningococcal meningitis. Demographic and clinical data were collected through interview and medical chart review. Antisera and monoclonal antibodies were used to determine the serogroup and serotype: serosubtype of the isolates, respectively. Surveillance identified a total of 408 cases of meningococcal meningitis, with a case fatality rate of 8% (32/397). The mean annual incidence for the 304 culture-positive cases residing in metropolitan Salvador was 1.71 cases per 100 000 population. Infants <1 year old presented the highest incidence (14.7 cases per 100 000 population). Of the 377 serogrouped isolates, 82%, 16%, 2% and 0.3% were serogroups B, C, W135 and Y, respectively. A single serotype:serosubtype (4,7:P1.19,15) accounted for 64% of all cases. Continued surveillance is necessary to characterise strains and to define future prevention and control strategies.
London
