Author(s):
Nascimento, Jéferson Chagas do ; David, Jorge Mauricio ; Barbosa, Luiz Cláudio de Almeida ; Paula, Vanderlucia Fonseca de ; Demuner, Antonio J. ; David, Juceni Pereira de Lima ; Conserva, Lucia Maria ; Ferreira Junior, Jésu Costa ; Guimarães, Elsie Franklin ; Nascimento, Jéferson Chagas do ; David, Jorge Mauricio ; Barbosa, Luiz Cláudio de Almeida ; Paula, Vanderlucia Fonseca de ; Demuner, Antonio J. ; David, Juceni Pereira de Lima ; Conserva, Lucia Maria ; Ferreira Junior, Jésu Costa ; Guimarães, Elsie Franklin
Date: 2014
Origin: Oasisbr
Subject(s): Piper klotzschianum; Piperaceae; Aedes aegypti; Larvicidal activity; Cytotoxic activities
Description
Texto completo: acesso restrito. p. 1267–1271
Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-04-15T12:57:31Z No. of bitstreams: 1 ps3495.pdf: 90399 bytes, checksum: 271ce1249a06193d7d73dc0eca1d25c4 (MD5)
Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-04-15T12:57:31Z No. of bitstreams: 1 ps3495.pdf: 90399 bytes, checksum: 271ce1249a06193d7d73dc0eca1d25c4 (MD5)
Made available in DSpace on 2014-04-15T12:57:31Z (GMT). No. of bitstreams: 1 ps3495.pdf: 90399 bytes, checksum: 271ce1249a06193d7d73dc0eca1d25c4 (MD5) Previous issue date: 2013
Made available in DSpace on 2014-04-15T12:57:31Z (GMT). No. of bitstreams: 1 ps3495.pdf: 90399 bytes, checksum: 271ce1249a06193d7d73dc0eca1d25c4 (MD5) Previous issue date: 2013
Background: Volatile oils from fresh roots, stems, leaves and seeds of Piper klotzschianum (Piperaceae) were obtained by hydrodistillation and analysed by GC-FID and GC-MS. In total, 25 components, representing more than 95% of the examined oils, were identified. The essential oils were evaluated against Artemia salina Leach nauplii and fourth-instar Aedes aegypti larvae. Results: The major chemical constituents that were identified from various parts of this plant were 1-butyl-3,4-methylenedioxybenzene and 2,4,5-trimethoxy-1-propenylbenzene in the root, 1-butyl-3,4-methylenedioxybenzene in the stems and leaves and 1-butyl-3,4-methylenedioxybenzene, limonene and α-phellandrene in the seeds. The biological activities of these essential oils generally exhibited high toxicity against A. salina, with LC50 values that ranged from 7.06 to 15.43 µg mL−1, and significant larvicidal activity against fourth-instar A. aegypti larvae was observed in the essential oils from the seeds (LC50 of 13.27 µg mL−1) and roots (LC50 of 10.0 µg mL−1) of the plant. Conclusion: The present study indicates that both essential oil of P. klotzsdhianum and the isolate 1-butyl-3,4-methylenedioxybenzene are potential resources for A. aegypti larva control. This is the first report of the biological activities of the oil and isolated compound. © 2013 Society of Chemical Industry
