Clustering of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and infective dermatitis associated with HTLV-1 (IDH) in Salvador, Bahia, Brazil

• Author(s): Silva, José Lucas Sena da ; Leite Primo, Janeusa Rita ; Oliveira, Maria de Fátima Santos Paim de ; Batista, Everton da Silva ; Carvalho, Otavio Augusto Moreno de ; Farré, Lourdes ; Bittencourt, Achilea Candida Lisboa ; Silva, José Lucas Sena da ; Leite Primo, Janeusa Rita ; Oliveira, Maria de Fátima Santos Paim de ; Batista, Everton da Silva ; Carvalho, Otavio Augusto Moreno de ; Farré, Lourdes ; Bittencourt, Achilea Candida Lisboa
• Date: 2014
• Origin: Oasisbr
• Subject(s): HTLV-1 infection; Clustering of HTLV-1-associated diseases; HTLV-1 associated myelopathy/tropical spastic paraparesis; Infective dermatitis associated with HTLV-1; HTLV-1 vertical transmission
• Document Type: Journal article
• Language: English

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Texto completo: acesso restrito. p. 482–485

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Fifteen families with clustering of infective dermatitis associated with HTLV-1 (IDH) and/or HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) were observed among 28 families of IDH index cases, 93% of them occurring in two generations. With the exception of two mothers of children with IDH, all the mothers with HAM/TSP had at least one child with HAM/TSP. This is the first report of such clustering involving many families.