Author(s): Ribeiro, Erika M. de O. ; Lima, Luciano S. ; David, Jorge Mauricio ; Vale, Ademir Evangelista do ; Lopes, Lucia M. Xavier ; David, Juceni Pereira de Lima ; Ribeiro, Erika M. de O. ; Lima, Luciano S. ; David, Jorge Mauricio ; Vale, Ademir Evangelista do ; Lopes, Lucia M. Xavier ; David, Juceni Pereira de Lima
Date: 2014
Origin: Oasisbr
Subject(s): Erythroxylum rimosum; Erythroxylaceae; Tropane alkaloid; Triterpenes; Acetylcholinesterase inhibition
Texto completo: acesso restrito. p. 232–235
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A new tropane alkaloid, named the 7β-acetoxy-3β,6β-dibenzoyloxytropane (1), was isolated from a methanol extract of Erythroxylum rimosum O.E. Schulz leaves. Other known compounds were detected, including quercetin, kaempferol-3-O-α-l-arabinofuranoside, (+)-catechin, epicatechin, quercetin-3-O-α-arabinofuranoside, quercetin-3-O-α-arabinopyranoside, quercetin-3-O-β-arabinopyranoside, quercetin-3-β-glucopyranoside, kaempferol, quercetin-3-O-β-galactopyranoside, β-sitosterol, α-amyrin, β-amyrin, and the ester derivatives of these two amyrins. Compound 1 exhibited weak inhibition of acetylcholinesterase. Structural identification was performed using IR, ESIHRMS and one- and two-dimensional NMR data analyses and confirmed by comparison with literature data.
