Detalhes do Documento

Predominance of Rotavirus Genotype G9 during the 1999, 2000, and 2002 Seasons among Hospitalized Children in the City of Salvador, Bahia, Brazil: Implications for Future Vaccine Strategies


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p. 4064–4069

Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2011-10-06T13:15:52Z No. of bitstreams: 1 0164-05.pdf: 133068 bytes, checksum: e402fac305525880f31683e48711b96a (MD5)

Made available in DSpace on 2011-10-06T13:15:52Z (GMT). No. of bitstreams: 1 0164-05.pdf: 133068 bytes, checksum: e402fac305525880f31683e48711b96a (MD5) Previous issue date: 2005-08

Two hundred eight of 648 (32%) diarrheal stool samples collected from hospitalized children under 5 years of age during a 3-year period (1999, 2000, and 2002) in the city of Salvador, in the state of Bahia, Brazil, were rotavirus positive. One hundred sixty-four of 208 (78.8%) rotavirus-positive samples had genotype G9 specificity, predominantly in association with P[8]. Other specificities detected were G1 (12.0%) and G4 (1.4%). Viruses with G2, G3, or P[4] specificity were not detected. Rotavirus genotype G9 predominated during each of the three seasons studied; it represented 89.2% of rotavirus strains detected in 1999, 85.3% in 2000, and 74.5% in 2002. G1 viruses (the globally most common G type) have a unique epidemiological characteristic of maintaining predominance during multiple consecutive rotavirus seasons. We have shown in this study for the first time that the G9 viruses also have a similar epidemiological characteristic, albeit for a shorter period of surveillance. The next generation of rotavirus vaccines will need to provide adequate protection against disease caused by G9 viruses.

Tipo de Documento Artigo científico
Idioma Inglês
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