Autor(es):
Silva, Aída Cristina do Nascimento ; Ferrazoli, Lucilaine ; Simonsen, Vera ; Reis, Joice Neves ; Pereira, Susan Martins ; Carmo, Theomira Mauadie Azevedo ; Mota, Eduardo Luiz Andrade ; Reis, Mitermayer Galvão ; Silva, Aída Cristina do Nascimento ; Ferrazoli, Lucilaine ; Simonsen, Vera ; Reis, Joice Neves ; Pereira, Susan Martins ; Carmo, Theomira Mauadie Azevedo ; Mota, Eduardo Luiz Andrade ; Reis, Mitermayer Galvão
Data: 2012
Origem: Oasisbr
Assunto(s): Tuberculosis; Molecular Epidemiology; Genetic Variation; Mycobacterium tuberculosis
Descrição
Submitted by Maria Creuza Silva (mariakreuza@yahoo.com.br) on 2012-01-26T12:21:48Z No. of bitstreams: 1 EMota 2011. Repositorio.pdf: 202435 bytes, checksum: 009495b8dcb57aeebecc6e1141216837 (MD5)
Made available in DSpace on 2012-01-26T12:21:48Z (GMT). No. of bitstreams: 1 EMota 2011. Repositorio.pdf: 202435 bytes, checksum: 009495b8dcb57aeebecc6e1141216837 (MD5) Previous issue date: 2011
This study constitutes a first attempt to describe the genetic population structure of Mycobacterium tuberculosis circulating in Salvador, Bahia State, Brazil. A total of 56 confirmed cases of pulmonary tuberculosis, identified between March and June 2008, were analyzed using restriction fragment length polymorphism (IS6110-RFLP). The study population was characterized by a predominance of males (71.43%) over 30 years of age (68.75%). Forty-one isolates were found to belong to a single pattern (73.2%), while 15 (26.7%) were found in group patterns, forming six clusters. The higher level of diversity observed is much more suggestive of endogenous reactivation than recent transmission.
São Paulo
