Autor(es):
Dourado, Maria Inês Costa ; Milroy, Craig A. ; Mello, Marco Antônio Gomes ; Ferradp, Geraldo Argolo ; Lima Filho, Humberto Castro ; Guimarães, Monick Lindenmeyer ; Morgado, Mariza Gonçalves ; Teixeira, Maria da Glória Lima Cruz ; Barreto, Mauricio Lima ; Castro, Bernardo Galvão ; Dourado, Maria Inês Costa ; Milroy, Craig A. ; Mello, Marco Antônio Gomes ; Ferradp, Geraldo Argolo ; Lima Filho, Humberto Castro ; Guimarães, Monick Lindenmeyer ; Morgado, Mariza Gonçalves ; Teixeira, Maria da Glória Lima Cruz ; Barreto, Mauricio Lima ; Castro, Bernardo Galvão
Data: 2012
Origem: Oasisbr
Assunto(s): HIV-1; HIV Seroprevalence; Cross-sectional Studies; Soroprevalência de HIV; Estudos Transversais
Descrição
Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2012-06-29T15:01:09Z No. of bitstreams: 1 WWW1535.pdf: 104154 bytes, checksum: e30ef20d939b8e5d747e8be7ab67b4b6 (MD5)
Made available in DSpace on 2012-06-29T15:01:09Z (GMT). No. of bitstreams: 1 WWW1535.pdf: 104154 bytes, checksum: e30ef20d939b8e5d747e8be7ab67b4b6 (MD5) Previous issue date: 2007
To estimate HIV-1 seroprevalence in the general population of Salvador, Bahia, Brazil, we conducted a cross-sectional survey of 3,437 residents from 1998 to 2000. Subjects were drawn from 30 sentinel areas representing a wide range of living conditions. Plasma samples were screened for HIV-1 antibodies by ELISA and confirmed by immunofluorescent assay. Subtype determination by HMA was performed after proviral DNA amplification. Phylogenetic analysis using parsimony was performed with the neighbor-joining method. Overall HIV-1 seroprevalence was 0.55% (19/3,446): 0.8% for men and 0.36% for women. Seroprevalence was higher in the 31-45-year age group (1%) and among persons with family income less than twice the minimum wage (0.78%) as compared to 0.33% for the higher income group. Syphilis was detected in 37% of HIV seropositive individuals. Phylogenetic inferences identified 10 samples as subtype B in the env region and 2 samples with Benv/Fgag/Fpol and Fenv/Bgag. Age > 30 years, male gender, and income < 2 times the minimum wage were identified as risk factors for HIV-1 infection. Extrapolating the proportion of seropositive individuals to Salvador, the number of HIV-1 infected individuals was estimated at 13,750.
Rio de Janeiro
