Autor(es): Gomes, Alcir Teixeira ; Honda, Neli Kika ; Roese, Fernanda Mesquita ; Muzzi, Rozanna Marques ; Marques, Maria Rita
Data: 2012
Origem: Oasisbr
Assunto(s): Ácidos; Química Orgânica; Compostos Orgânicos; Farmacognosia; Acids; Organic Chemistry; Organic Compounds; Pharmacognosy
With the aim of obtaining new compounds with potential antifungal activity, lecanoric acid, a chemical constituent of the lichen Parmotrema tinctorum and its derivatives prepared from structural modification were tested against the fungus Cladosporium sphaerospermum, by employing the bioautographic method. Activity of the derivatives ranged from 10- to 1-μg concentrations. Results demonstrated this series of compounds to have potent fungitoxic activity.
