Document details

Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A

Author(s): Santos, Edson dos Anjos dos ; Beatriz, Adilson ; Lima, Dênis Pires de ; Marques, Maria Rita ; Leite, Carla Braga

Date: 2011

Origin: Oasisbr

Subject(s): Alface; Germinação; Lipídeos; Lettuce; Germination; Lipids


Description

Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range.

Document Type Journal article
Language English
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