Global impact of the COVID-19 pandemic on stroke volumes and cerebrovascular events

• Autor(es): Nguyen, Thanh N. ; Qureshi, Muhammad M. ; Klein, Piers ; Yamagami, Hiroshi ; Mikulik, Robert ; Czlonkowska, Anna ; Abdalkader, Mohamad ; Sedova, Petra ; Sathya, Anvitha ; Lo, Hannah C. ; Mansour, Ossama Yassin ; Iversen, Helle Klingenberg ; Truelsen, Thomas Clement ; Wienecke, Troels ; Sobh, Khalid ; Ylikotila, Pauli ; Alpay, Kemal ; Strbian, Daniel ; Bernady, Patricia ; Casenave, Philippe ; Dan, Maria ; Vanguru, Husitha Reddy ; Faucheux, Jean-Marc ; Gentric, Jean-Christophe ; Magro, Elsa ; Sabben, Candice ; Reiner, Peggy ; Rouanet, Francois ; Bohmann, Ferdinand O. ; Boskamp, Stefan ; Mbroh, Joshua ; Nagel, Simon ; Lesaine, Emilie ; Nolte, Christian H. ; Ringleb, Peter A. ; Rosenkranz, Michael ; Poli, Sven ; Thomalla, Götz ; Karapanayiotides, Theodoros ; Koutroulou, Ioanna ; Kargiotis, Odysseas ; Palaiodimou, Lina ; Barrientos Guerra, Jose Dominguo ; Tsivgoulis, Georgios ; Huded, Vikram ; Menon, Bindu ; Nagendra, Shashank ; Prajapati, Chintan ; Sylaja, P.N. ; Krishna Pramana, Nyoman Angga ; Sani, Achmad Firdaus ; Ghoreishi, Abdoreza ; Farhoudi, Mehdi ; Hokmabadi, Elyar Sadeghi ; Loochtan, Aaron I. ; Raya, Tariq Abu ; Kalmanovich, Shani Avnery ; Ronen, Levite ; Sabetay, Sergiu Ionut ; Acampa, Maurizio ; Adami, Alessandro ; Castellan, Lucio ; Longoni, Marco ; Ornello, Raffaele ; Renieri, Leonardo ; Demeestere, Jelle ; Bigliani, Claudia Rolla ; Romoli, Michele ; Sacco, Simona ; Salmaggi, Andrea ; Sangalli, Davide ; Zini, Andrea ; Doijiri, Ryosuke ; Fukuda, Hiroki ; Fujinaka, Toshiyuki ; Fujita, Kyohei ; Uchino, Ken ; Imamura, Hirotoshi ; Sakai, Nobuyuki ; Kanamaru, Takuya ; Kimura, Naoto ; Kono, Ryuhei ; Miyake, Kosuke ; Sakaguchi, Manabu ; Sakai, Kenichiro ; Sonoda, Kazutaka ; Todo, Kenichi ; Inoa, Violiza ; Miyashita, Fumio ; Tokuda, Naoki ; Matsumaru, Yuji ; Matsumoto, Shoji ; Ohara, Nobuyuki ; Shindo, Seigo ; Takenobu, Yohei ; Yoshimoto, Takeshi ; Toyoda, Kazunori ; Uwatoko, Takeshi ; Goyal, Nitin ; Yagita, Yoshiki ; Yamada, Takehiro ; Yamamoto, Nobuaki ; Yamamoto, Ryoo ; Yazawa, Yukako ; Sugiura, Yuri ; Waweru, Peter Kuria ; Baek, Jang-Hyun ; Lee, Si Baek ; Seo, Kwon-Duk ; Charidimou, Andreas ; Sohn, Sung-Il ; Arsovska, Anita Ante ; Chan, Yong Chieh ; Wan Zaidi, Wan Asyraf ; Jaafar, Ainul Syahrilfazli ; Gongora-Rivera, Fernando ; Martinez-Marino, Manuel ; Infante-Valenzuela, Adrian ; Groppa, Stanislav ; Leahu, Pavel ; Siegler, James E. ; Coutinho, Jonathan M. ; Rinkel, Leon A. ; Dippel, Diederik W.J. ; van Dam-Nolen, Dianne H.K. ; Ranta, Annemarei ; Wu, Teddy Y. ; Adebayo, Tajudeen Temitayo ; Bello, Abiodun H. ; Nwazor, Ernest Okwundu ; Sunmonu, Taofiki Ajao ; Yaghi, Shadi ; Wahab, Kolawole Wasiu ; Ronning, Ole Morten ; Sandset, Else Charlotte ; Al Hashmi, Amal M. ; Ahmad, Saima ; Rashid, Umair ; Rodriguez-Kadota, Liliana ; Vences, Miguel Ángel ; Yalung, Patrick Matic ; Hao Dy, Jon Stewart ; de Sousa, Diana Aguiar ; Pineda-Franks, Maria Carissa ; Co, Christian Oliver ; Brola, Waldemar ; Debiec, Aleksander ; Dorobek, Malgorzata ; Karlinski, Michal Adam ; Labuz-Roszak, Beata M. ; Lasek-Bal, Anetta ; Sienkiewicz-Jarosz, Halina ; Staszewski, Jacek ; Mohammaden, Mahmoud H. ; Sobolewski, Piotr ; Wiacek, Marcin ; Zielinska-Turek, Justyna ; Araujo, Andre Pinho ; Rocha, Mariana ; Castro, Pedro ; Cruz, Vitor Tedim ; Ferreira, Paulo Venancio ; Ferreira, Patricia ; Nunes, Ana Paiva ; Haussen, Diogo C. ; Fonseca, Luisa ; Marto, João Pedro ; Melo, Teresa Pinho e ; Rodrigues, Miguel ; Silva, M. Luis ; Dimitriade, Adela ; Falup-Pecurariu, Cristian ; Hamid, May Adel ; Venketasubramanian, Narayanaswamy ; Krastev, Georgi ; Kristoffersen, Espen Saxhaug ; Mako, Miroslav ; Ayo-Martin, Oscar ; Hernández-Fernández, Francisco ; Blasco, Jordi ; Rodríguez-Vázquez, Alejandro ; Cruz-Culebras, Antonio ; Moniche, Francisco ; Montaner, Joan ; Perez-Sanchez, Soledad ; García Sánchez, María Jesús ; Lereis, Virginia Pujol ; Guillán Rodríguez, Marta ; Jood, Katarina ; Nordanstig, Annika ; Mazya, Michael V. ; Moreira, Tiago T.P. ; Bernava, Gianmarco ; Beyeler, Morin ; Bolognese, Manuel ; Carrera, Emmanuel ; Dobrocky, Tomas ; Scollo, Sergio Daniel ; Karwacki, Grzegorz Marek ; Keller, Emanuela ; Hsieh, Chang Yang ; Boonyakarnkul, Surawan ; Churojana, Anchalee ; Aykac, Ozlem ; Ozdemir, Atilla Özcan ; Bajrami, Arsida ; Senadim, Songul ; Hussain, Syed Irteza ; Campbell, Bruce C. V. ; John, Seby ; Banerjee, Soma ; Kwan, Joseph ; Krishnan, Kailash ; Lenthall, Robert ; Matthews, Ashok ; Wong, Ken ; Zhang, Liqun ; Altschul, Dorothea ; Asif, Kaiz S. ; Ma, Alice ; Bahiru, Zeelalem ; Below, Kristine ; Biller, José ; Ruland, Sean ; Chaudry, Saqib A. ; Chen, Michael ; Chebl, Alex ; Cibulka, Jackie ; Cistrunk, Leon ; Clark, Judith ; Thomas, James Orton ; Colasurdo, Marco ; Czap, Alexandra ; de Havenon, Adam ; D'Amato, Salvatore ; Dharmadhikari, Sushrut ; Grimmett, Kasey B. ; Dmytriw, Adam A. ; Etherton, Mark R. ; Ezepue, Chizoba ; Farooqui, Mudassir ; Parsons, Mark W. ; Feske, Steven K. ; Fink, Lauren ; Gasimova, Ulviyya ; Guzik, Amy K. ; Hakemi, Maryam ; Hovingh, Majesta ; Khan, Muhib ; Jillela, Dinesh ; Kan, Peter T. ; Khatri, Rakesh ; Singhal, Shaloo ; Khawaja, Ayaz M. ; Khoury, Naim N. ; Kiley, Nicole L. ; Kim, Benny S. ; Kolikonda, Murali K. ; Kuhn, Anna Luisa ; Lara, Stephanie ; Linares, Guillermo ; Linfante, Italo ; Lukovits, Timothy G. ; Slater, Lee-Anne ; Lycan, Sarah ; Male, Shailesh S. ; Maali, Laith ; Mancin, John ; Masoud, Hesham ; Mohamed, Ghada A. ; Monteiro, Andre ; Nahab, Fadi ; Nalleballe, Krishna ; Ortega-Gutierrez, Santiago ; Tomazini Martins, Rodrigo ; Puri, Ajit S. ; Radaideh, Yazan ; Rahangdale, Rahul H. ; Rai, Ansaar ; Ramakrishnan, Pankajavalli ; Reddy, Aravind B. ; Rojas-Soto, Diana M. ; Romero, Jose Rafael ; Rost, Natalia S. ; Rothstein, Aaron ; Enzinger, Chris ; Omran, Setareh Salehi ; Sheth, Sunil A. ; Siddiqui, Adnan H. ; Starosciak, Amy K. ; Tarlov, Nicholas E. ; Taylor, Robert A. ; Wang, Michael J. ; Wolfe, Jared ; Wong, Ka-Ho ; Le, Huynh Vu ; Gattringer, Thomas ; Nguyen, Quy Viet ; Pham, Thong Nhu ; Nguyen, Trung Thanh ; Phan, Hoang Thi ; Ton, Mai Duy ; Fischer, Urs ; Michel, Patrik ; Strambo, Davide ; Martins, Sheila O. ; Zaidat, Osama O. ; Rahman, Aminur ; Nogueira, Raul G. ; Bonnet, Thomas ; Ligot, Noemie ; De Raedt, Sylvie ; Lemmens, Robin ; Vanacker, Peter ; Vandervorst, Fenne ; Conforto, Adriana Bastos ; Hidalgo, Raquel C.T. ; de Oliveira Neves, Luciana ; Martins, Rodrigo Targa ; Mora Cuervo, Daissy Liliana ; Rebello, Leticia C. ; Santiago, Igor Bessa ; Lameirinhas da Silva, Isabelle ; Sakelarova, Teodora ; Kalpachki, Rosen ; Alexiev, Filip ; Catanese, Luciana ; Cora, Elena Adela ; Goyal, Mayank ; Hill, Michael D. ; Kelly, Michael E. ; Khosravani, Houman ; Lavoie, Pascale ; Peeling, Lissa ; Pikula, Aleksandra ; Rivera, Rodrigo ; Chen, Hui-Sheng ; Chen, Yimin ; Huo, Xiaochuan ; Miao, Zhongrong ; Yang, Shuiquan ; Bedekovic, Marina Roje ; Bralic, Marina ; Budincevic, Hrvoje ; Corredor-Quintero, Angel Basilio ; Lara-Sarabia, Osvaldo E. ; Cabal, Martin ; Tenora, Dusan ; Fibrich, Petr ; Herzig, Roman ; Hlaváčová, Helena ; Hrabanovska, Emanuela ; Hlinovsky, David ; Jurak, Lubomir ; Kadlcikova, Jana ; Karpowicz, Igor ; Klecka, Lukas ; Kovar, Martin ; Lauer, David ; Neumann, Jiri ; Palouskova, Hana ; Reiser, Martin ; Rekova, Petra ; Rohan, Vladimir ; Skoda, Ondrej ; Škorňa, Miroslav ; Sobotková, Lenka ; Sramek, Martin ; Zakova, Lenka ; Christensen, Hanne ; Drenck, Nicolas
• Data: 2023
• Identificador Persistente: http://hdl.handle.net/10451/56041
• Origem: Repositório da Universidade de Lisboa
• Tipo de Documento: Artigo científico
• Idioma: Inglês
• Contribuidor(es): Repositório Científico de Acesso Aberto da ULisboa

Descrição

Background and objectives: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020). Methods: We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. Results: There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1-6.9]; p < 0.0001). ICH volumes declined from 29,585 to 28,156 (4.8% [5.1-4.6]; p < 0.0001) and IVT volume from 24,584 to 23,077 (6.1% [6.4-5.8]; p < 0.0001). Larger declines were observed at high-volume compared with low-volume centers (all p < 0.0001). There was no significant change in mechanical thrombectomy volumes (0.7% [0.6-0.9]; p = 0.49). Stroke was diagnosed in 1.3% [1.31-1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82-2.97], 5,656/195,539) of all stroke hospitalizations. Discussion: There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year.