A twist to splicing regulation in haematopoiesis

• Author(s): Carmo-Fonseca, Maria
• Date: 2023
• Persistent ID: http://hdl.handle.net/10451/57106
• Origin: Repositório da Universidade de Lisboa
• Document Type: Journal article
• Language: English
• Contributor(s): Repositório Científico de Acesso Aberto da ULisboa

Description

DNMT3A is best known for its de novo DNA methyltransferase activity. But a new study shows that the protein also has a role in RNA splicing during activation of embryonic and haematopoietic stem cells. This introduces a new perspective for approaching diseases associated with DNMT3A mutations.