Autor(es): Cruz, Helena Medina ; Scalioni, Leticia de Paula ; Paula, Vanessa Salete de ; Miguel, Juliana Custódio ; Ó, Kycia Maria Rodrigues do ; Milagres, Flavio Augusto Pádua ; Cruz, Marcelo Santos ; Bastos, Francisco Inácio ; Flores, Priscila Pollo ; Leal, Erotildes ; Motta-Castro, Ana Rita Coimbra ; Lewis-Ximenez, Lia Laura ; Lampe, Elisabeth ; Villar, Livia Melo
Data: 2018
Origem: Oasisbr
Assunto(s): Hepatite B; Anticorpos
Rapid tests (RTs) can be used as an alternative method for the conventional diagnosis of hepatitis B virus (HBV). This study aims to evaluate antibodies to HBsAg (anti-HBs) and antibodies to HBeAg (anti-HBe) RTs under different Brazilian settings. The following three groups were included: GI: viral hepatitis outpatient services; GII: low resource areas; and GIII: crack users and beauticians. Imuno-rápido anti-HBsAg™ and Imuno-rápido anti-HBeAg™ RTs were evaluated and showed specificities greater than 95% in all groups. The sensitivity values to anti-HBs were 50.38%, 51.05% and 46.73% and the sensitivity values to anti-HBe were 76.99%, 10.34% and 11.76% in the GI, GII and GIII groups, respectively. The assays had a low sensitivity and high specificity, which indicated their use for screening in regions endemic for HBV.
