Author(s): Babboni, Selene Daniela [UNESP] ; Costa, Heni Falcao da [UNESP] ; Alves Martorelli, Luzia de Fatima ; Arruda Geraldes Kataoka, Ana Paula de ; Victória, Cassiano [UNESP] ; Padovani, Carlos Roberto [UNESP] ; Modolo, José Rafael [UNESP]
Date: 2015
Persistent ID: http://hdl.handle.net/11449/117321
Origin: Oasisbr
Subject(s): Rabies; Dogs; Vaccination; Revaccination; Annual vaccination campaign; Fuenzalida-Palacios
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Background: Rabies, a zoonosis found throughout the globe, is caused by a virus of the Lyssavirus genus. The disease is transmitted to humans through the inoculation of the virus present in the saliva of infected mammals. Since its prognosis is usually fatal for humans, nationwide public campaigns to vaccinate dogs and cats against rabies aim to break the epidemiological link between the virus and its reservoirs in Brazil.Findings: During 12 months we evaluated the active immunity of dogs first vaccinated (booster shot at 30 days after first vaccination) against rabies using the Fuenzalida-Palacios modified vaccine in the urban area of Botucatu city, Sao Pauto state, Brazil. Of the analyzed dogs, 54.7% maintained protective titers (>= 0.5 IU/mL) for 360 days after the first vaccination whereas 51.5% during all the study period.Conclusions: The present results suggest a new vaccination schedule for dogs that have never been vaccinated. In addition to the first dose of vaccine, two others are recommended: the second at 30 days after the first and the third dose at 180 days after the first for the maintenance of protective titers during 12 months.
Sao Paulo State Univ, Univ Estadual Paulista, UNESP, Sch Vet Med & Anim Husb,Dept Vet Hyg & Publ Hlth, Botucatu, SP, Brazil
Sao Paulo State Univ, Univ Estadual Paulista, UNESP, Sch Vet Med,Dept Anim Hlth & Prod, Aracatuba, SP, Brazil
Ctr Control Zoonosis Sao Paulo City, Lab Zoonoses & Vector Borne Dis, Sao Paulo, Brazil
Sao Paulo State Univ, Univ Estadual Paulista, UNESP, Dept Biostat,Botucatu Biosci Inst, Botucatu, SP, Brazil
Sao Paulo State Univ, Univ Estadual Paulista, UNESP, Sch Vet Med & Anim Husb,Dept Vet Hyg & Publ Hlth, Botucatu, SP, Brazil
Sao Paulo State Univ, Univ Estadual Paulista, UNESP, Sch Vet Med,Dept Anim Hlth & Prod, Aracatuba, SP, Brazil
Sao Paulo State Univ, Univ Estadual Paulista, UNESP, Dept Biostat,Botucatu Biosci Inst, Botucatu, SP, Brazil
FAPESP: 09-09098-8
